A study was conducted to observe the effect Metformin had on maintaining muscle glycogen inside muscle fibers and stabilizing muscle weight during inactivity of muscles in test rats. This study was done using three different methods of measurement of metabolic rate. The first group was observed in an inactive state in a metabolic chamber and the second were observed in an active/non-active state in a metabolic chamber, metformin weight loss. The third group was observed in an inactive state in an open field. The results of this study showed no effect of Metformin on glycogen concentration in a muscle fiber, weight metformin loss. However, Metformin enhanced muscle activation of glucose-dependent insulinotropic polypeptide (GIP) in muscle fibers, best uk steroid labs 2022. So, the results of this study indicated that Metformin had no effect on muscle function.